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Derma Botanica's 4 Step Night Routine consisting of the Overnight Repair Serum, AHA & BHA Exfoliating Cleanser, Moisture-Locking Face Oil and Adaptogenic Soothing Cream
Derma Botanica Overnight Repair Serum bottle with text highlighting its benefits on a white background
Derma Botanica Overnight Repair Serum is held by a hand, with product benefits displayed in a clinical study.
Derma Botanica Overnight Repair Serum before and after comparison in the reduction of fine lines and wrinkles.
Derma Botanica Overnight Repair Serum before and after comparison of skin tone with text indicating improvement.
AHA & BHA Exfoliating Cleanser with labeled ingredients on a white background
Derma Botanica AHA & BHA Exfoliating Cleanser with text highlighting its benefits on a white background
Derma Botanica Moisture-Locking Face Oil droplet with text listing ingredients on a white background
Derma Botanica Moisture-Locking Face Oil with text highlighting its benefits on a white background
Adaptogenic Soothing Cream with labeled ingredients on a white background
Derma Botanica Adaptogenic Soothing Cream with text on benefits on a light background

The 4-Step Night Routine

A complete non-retinol routine for glow, hydration, and skin renewal.
4.7 (419 reviews)

Ideal for dry, sensitive, or mature skin, it’s perfect for anyone following a retinol-free routine but still wanting visible anti-aging results.

This 4-step ritual clears buildup, hydrates, soothes, and locks in moisture to improve the appearance of fine lines, uneven tone, and loss of firmness. By morning, skin feels smoother, firmer, and more radiant with a refreshed glow.

  • Clears buildup and smooths texture for a fresh, refined look
  • Delivers deep hydration to plump skin and reduce visible signs of aging
  • Calms irritation and locks in moisture to strengthen the barrier and restore balance
Free Exfoliating Cleanser worth $47
With every $100+ purchase
Regular price$213.00 Sale price$181.00
Regular price Save 15%
60-Day Money-Back Guarantee

60-Day Money-Back Guarantee

See visible results after 60 days or your money back — even if the bottle’s empty.

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Free US Shipping Over $50

No hidden fees. Free delivery across the US mainland.

Dermatologist Developed

Dermatologist Developed

Expertly formulated with scientifically proven actives.

4 Steps. 1 Night Routine. Formulated to Work Together.

Each step in this system is designed to complement the next so you get smoother, stronger, brighter skin without irritation, dryness, or overload.

Step 1: Cleanse & Prep

AHA & BHA Exfoliating Cleanser

AHA & BHA Exfoliating Cleanser

Step 1: Cleanse & Prep

AHA & BHA Exfoliating Cleanser

The first step in your nighttime routine, this cleanser combines Glycolic Acid (AHA) and White Willow Bark (BHA) to gently exfoliate, clear congested skin, and refine uneven texture. Aloe Essence and Shea Butter maintain hydration, while Bilberry Extract and Vitamin E provide antioxidant protection, leaving skin clean, balanced, and ready for the next steps in your routine.

The result: Skin that looks smoother, clearer, and visibly more radiant.

  • Clears impurities and removes pore buildup
  • Smooths rough texture for a refined look
  • Brightens dullness for a more even tone
  • Preps skin to absorb active ingredients more effectively
What's Inside

  • Glycolic Acid (AHA) + White Willow Bark (BHA)

    A gentle yet effective duo that unclogs pores, refines texture, and smooths roughness. Glycolic Acid resurfaces and brightens, while White Willow Bark reduces buildup for a clearer-looking complexion.

  • Aloe Essence + Shea Butter

    Hydrates and soothes to keep skin comfortable after cleansing. Aloe delivers lightweight hydration, while Shea Butter nourishes and softens for a balanced, supple feel.

  • CalmResilience™ Complex

    Our proprietary adaptogen blend of Centella, Ashwagandha, and Amla helps calm visible irritation and supports a stronger skin barrier during daily exfoliation.

  • Bilberry Extract + Vitamin E

    Antioxidant-rich botanicals that help defend against environmental stress, support a more even-looking tone, and soften the appearance of early fine lines.

Dr. Randi Goldstein
Dr. Randi Goldstein MD, FAAD, Board‑Certified Dermatologist
"In my experience, patients get the best results when their routines are simple and easy to stick to. Derma Botanica’s multi-functional formulas reduce the number of products needed, making consistency easy, without compromising on efficacy."

What you'll notice

Week 1

Skin begins to look clearer, calmer, and more hydrated, with texture starting to feel smoother and a fresh, rested glow each morning.

Week 2-4

Texture looks smoother and more refined, fine lines appear softened, and tone looks more even. Skin feels deeply nourished, balanced, and naturally radiant.

Ongoing Use

Hydration stays locked in, wrinkles appear visibly reduced, and skin looks firmer, clearer, and more youthful with long-lasting radiance.

Kellys’s Journey | Duration 4 weeks

“I’ve been using this serum as part of my routine, and it’s made such a difference. My skin feels more hydrated and has a healthy brightness in the morning. I usually have a hard time with products that contain actives because my skin is so sensitive, but this one hasn’t caused any irritation at all.”

Nicole’s Journey | Duration 8 weeks

“I love this serum. My skin feels more hydrated when I wake up and looks brighter overall. The dark spots on my cheeks have faded too, which I honestly didn’t expect. Since my skin is sensitive, I usually can’t handle products with strong actives, but this one has been gentle and soothing.”

Camila's Journey | Duration 1 Month

“I’ve always struggled with dark spots and skin that looked dull. After a month of using this serum, my skin looks brighter and clearer. The spots on my face have begun to fade, and my skin feels smoother with a healthy glow. It’s the first time I can honestly say I’m seeing real results.”

Carmen’s Journey | Duration 2 weeks

“This left my skin feeling deeply moisturized and helped smooth out the uneven areas I’ve always struggled with. I wasn’t expecting a big transformation, so the results really surprised me. It’s definitely become one of those products I’d 100% recommend to anyone.”

Hannah's Journey | Duration 3 Months

“My skin always looked red, irritated, and tight no matter what I tried. After consistently using this serum, the redness completely calmed down and my skin feels comfortable again. It looks much plumper and healthier. For the first time in a long while, I actually feel good about my skin.”

Jessica's Journey | Duration 6 Weeks

"Six weeks in and my skin looks so much smoother. The rough texture around my cheeks has softened, and overall my skin feels calmer and more balanced. I’ve tried a lot of serums before, but this is the first one that gave me visible results without irritation."

Good to know

Clean formula | Safe for all skin types | No parabens, sulfates, phthalates, or synthetic dyes | Non-comedogenic | Vegan | Cruelty-free

AHA & BHA Exfoliating Cleanser

Water/Aqua/Eau, Cocamidopropyl Betaine, Decyl Glucoside, Cetearyl Alcohol, Glycerin, Elaeis
Guineensis (Palm) Oil, Phenoxyethanol, Helianthus Annuus (Sunflower) Seed Oil, Prunus Armeniaca (Apricot) Kernel Oil, Glycolic Acid, Butyrospermum Parkii (Shea) Butter, Mangifera Indica (Mango) Seed Butter, Polysorbate 60, Malic Acid, Centella Asiatica Leaf Extract, Phyllanthus Emblica Fruit Extract, Withania Somnifera Root Extract, Salix Alba (White Willow) Extract, Xanthan Gum, Tetrasodium Glutamate Diacetate, Aloe Barbadensis Leaf Juice, Tocopherol Acetate, Organic Vaccinium Myrtillus (Bilberry) Extract, Fragrance (Parfum), Copper Chlorophyllin.


Overnight Repair Serum

Water/Aqua/Eau, Glycerin, Centella Asiatica Leaf Extract, Phyllanthus Emblica Fruit Extract,
Withania Somnifera Root Extract, Propanediol, Niacinamide, Butylene Glycol, Glycosphingolipids, Phenoxyethanol, Oryza Sativa (Rice) Lipids, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Hyaluronate, Hydrolyzed Glycosaminoglycans, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Tremella Fuciformis Polysaccharide, Polyglutamic Acid, Mandelic Acid, Aspartic Acid, Gluconolactone, Lactobionic Acid, Pseudoalteromonas Exopolysaccharides, Hydrolyzed Soy Protein, Rice Amino Acids, Hydrolyzed Adansonia Digitata Seed Extract, Proline, Tocopherol Acetate, Squalane, Bakuchiol, Oenothera Biennes Oil, Panthenol, Sodium Benzoate, Potassium Sorbate, Fragrance (Parfum).

Adaptogenic Soothing Cream

Water/Aqua/Eau, Helianthus Annuus (Sunflower) Seed Oil, Cetearyl Alcohol, Polysorbate 60, Rosa Damascena (Rose) Flower Distillate, Glycerin, Helianthus Annuus (Sunflower) Seed Oil, Centella Asiatica Leaf Extract, Phyllanthus Emblica Fruit Extract, Withania Somnifera Root Extract, Cocos Nucifera (Coconut) Oil, Stearic Acid, Squalane, Phenoxyethanol, Simmondsia Chinensis (Jojoba) Seed Oil, Tocopherol Acetate, Dimethylaminoethanol, Methyl Sulfonyl Methane, Xanthan Gum, Aloe Barbadensis Leaf Juice, Propylene Glycol, Aspalathus Linearis (Rooibus) Leaf Extract, Sodium Hyaluronate, Fragrance (Parfum).


Moisture-Locking Face Oil

Helianthus Annuus (Sunflower) Seed Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Salvia
Hispanica (Chia) Seed Oil, Centella Asiatica Leaf Extract, Phyllanthus Emblica Fruit Extract, Withania Somnifera Root Extract, Sclerocarya Birrea (Marula) Oil, Squalane, Oryza Sativa (Rice) Lipids, Euterpe Oleracea Sterols, Linoleic Acid, Oleic Acid, Linolenic Acid, Hippophae Rhamnoides Oil, Tocopherol Acetate, Bisabolol, Fragrance (Parfum).

4 Steps. 1 Night Routine. Formulated to Work Together.

Each step in this system is designed to complement the next so you get smoother, stronger, brighter skin without irritation, dryness, or overload.

Step 1: Cleanse & Prep

AHA & BHA Exfoliating Cleanser

AHA & BHA Exfoliating Cleanser

Step 1: Cleanse & Prep

AHA & BHA Exfoliating Cleanser

The first step in your nighttime routine, this cleanser combines Glycolic Acid (AHA) and White Willow Bark (BHA) to gently exfoliate, clear congested skin, and refine uneven texture. Aloe Essence and Shea Butter maintain hydration, while Bilberry Extract and Vitamin E provide antioxidant protection, leaving skin clean, balanced, and ready for the next steps in your routine.

The result: Skin that looks smoother, clearer, and visibly more radiant.

  • Clears impurities and removes pore buildup
  • Smooths rough texture for a refined look
  • Brightens dullness for a more even tone
  • Preps skin to absorb active ingredients more effectively
What's Inside

  • Glycolic Acid (AHA) + White Willow Bark (BHA)

    A gentle yet effective duo that unclogs pores, refines texture, and smooths roughness. Glycolic Acid resurfaces and brightens, while White Willow Bark reduces buildup for a clearer-looking complexion.

  • Aloe Essence + Shea Butter

    Hydrates and soothes to keep skin comfortable after cleansing. Aloe delivers lightweight hydration, while Shea Butter nourishes and softens for a balanced, supple feel.

  • CalmResilience™ Complex

    Our proprietary adaptogen blend of Centella, Ashwagandha, and Amla helps calm visible irritation and supports a stronger skin barrier during daily exfoliation.

  • Bilberry Extract + Vitamin E

    Antioxidant-rich botanicals that help defend against environmental stress, support a more even-looking tone, and soften the appearance of early fine lines.

Routine FAQs

Customer Reviews

Based on 419 reviews
86%
(362)
7%
(29)
6%
(25)
1%
(3)
0%
(0)
T
Tammy R.
A little goes a long way

1-2 drops and I’m good. Lasts ages. Worth the $

C
Christina
LOVE THIS STUFF!!!

No irritation, no dryness, just glowy happy skin. What else do u need in a serum??

D
Danielle
Best part of my night routine now

Coming home, taking off makeup with this, and feeling that fresh smooth skin after… it’s honestly become my favorite moment of the day 🫶 love the vibe and how clean my face feels.

m
maya
Glassy skin vibes

Smooth, soft, shiny (in a good way). Looks like I used a filter.

J
Jade s.
Moisture bomb!!

This plumps my skin so nicely. Lines on my forehead are WAY less visible. Looks airbrushed.

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We believe you deserve visible results: smoother, firmer, younger-looking skin that helps you feel confident every time you look in the mirror. That’s why every purchase is backed by our 60-day money-back guarantee. If you don’t love how your skin looks and feels, just send it back and get a full refund. No questions asked—even if the bottles are empty.

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