Overnight Retinol Serum Usage Instructions
Patch Test
Before using the Overnight Retinol Serum on your face, apply a small amount on a discreet area (e.g., behind your ear or jawline) for 24-48 hours to check for any irritation.
Note: You cannot use the Overnight Retinol Serum if you’re pregnant or breastfeeding.
How Often to Apply
For the best results, use every night. If there is any irritation, reduce the number of nights you use it per week.
How to Apply
Apply at night:
1. Cleanse your face with a gentle, non-active cleanser
2. Allow your skin to fully dry before applying
3. Apply 2–3 pumps to your face and spread a thin, even layer, avoiding the eye area, corners of the mouth, and around the nostrils
4. Wait 10–20 minutes before applying a hydrating moisturizer
5. In the morning, apply SPF 30 or higher since retinol can increase sun sensitivity
Allowed vs Not Allowed Skincare Products During Study
Allowed Products |
Not Allowed Products |
Gentle, non-active cleanser |
Any product containing retinol, retinal, or retinoids |
Basic moisturizer (no actives) |
Vitamin C or brightening serums |
Broad-spectrum sunscreen (SPF 30+) |
AHAs/BHAs (glycolic acid, lactic acid, salicylic acid) |
Hydrating toner or mist (non-exfoliating) |
Peptides, growth factors, serums or creams |
Eye cream (non-active) |
Anti-aging serums or creams |
Lip balm or facial oil (no essential oils or actives) |
High-strength niacinamide (above 5%) |
Sheet masks (hydrating only) |
Spot treatments with acids or actives |
Makeup (optional, must be removed before photos) |
Exfoliating scrubs or physical exfoliants |
In-office treatments (chemical peels, microneedling, lasers) |
|
Facial tools (LED masks, microcurrent, dermaplaning, etc.) |
|
New products (other than those provided in the study) |